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Concept
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Insulin Resistance
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Academic Article
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Seminars in Medicine of the Beth Israel Hospital, Boston. Non-insulin-dependent diabetes mellitus - a genetically programmed failure of the beta cell to compensate for insulin resistance.
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Academic Article
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Clinical phenotypes, insulin secretion, and insulin sensitivity in kindreds with maternally inherited diabetes and deafness due to mitochondrial tRNALeu(UUR) gene mutation.
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Academic Article
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Effects of morning cortisol elevation on insulin secretion and glucose regulation in humans.
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Academic Article
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Elevated plasma glucose 2 h postchallenge predicts defects in beta-cell function.
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Academic Article
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Alterations in the glucose-stimulated insulin secretory dose-response curve and in insulin clearance in nondiabetic insulin-resistant individuals.
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Academic Article
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Changes in pancreatic islet glucokinase and hexokinase activities with increasing age, obesity, and the onset of diabetes.
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Academic Article
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Troglitazone improves defects in insulin action, insulin secretion, ovarian steroidogenesis, and fibrinolysis in women with polycystic ovary syndrome.
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Academic Article
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Maturity onset diabetes of the young (MODY).
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Academic Article
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Metabolic effects of troglitazone monotherapy in type 2 diabetes mellitus. A randomized, double-blind, placebo-controlled trial.
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Academic Article
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Interactions between insulin resistance and insulin secretion in the development of glucose intolerance.
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Academic Article
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Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat.
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Academic Article
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Dynamics of insulin secretion in obesity and diabetes.
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Academic Article
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Roles of insulin resistance and obesity in regulation of plasma insulin concentrations.
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Academic Article
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Insulin release in impaired glucose tolerance: oral minimal model predicts normal sensitivity to glucose but defective response times.
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Academic Article
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Oral glucose tolerance test minimal model indexes of beta-cell function and insulin sensitivity.
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Academic Article
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Impaired beta-cell compensation to dexamethasone-induced hyperglycemia in women with polycystic ovary syndrome.
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Academic Article
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Defective insulin secretion and increased susceptibility to experimental diabetes are induced by reduced Akt activity in pancreatic islet beta cells.
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Academic Article
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Insulin sensitivity by oral glucose minimal models: validation against clamp.
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Academic Article
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Rosiglitazone reduces glucose-stimulated insulin secretion rate and increases insulin clearance in nondiabetic, insulin-resistant individuals.
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Academic Article
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Retinol-binding protein 4, insulin resistance, and type 2 diabetes.
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Academic Article
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Kir6.2 variant E23K increases ATP-sensitive K+ channel activity and is associated with impaired insulin release and enhanced insulin sensitivity in adults with normal glucose tolerance.
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Academic Article
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Two-hour seven-sample oral glucose tolerance test and meal protocol: minimal model assessment of beta-cell responsivity and insulin sensitivity in nondiabetic individuals.
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Academic Article
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Weight loss therapy improves pancreatic endocrine function in obese older adults.
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Academic Article
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Ginsenoside Re rapidly reverses insulin resistance in muscles of high-fat diet fed rats.
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Academic Article
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Insulin secretory defects in polycystic ovary syndrome. Relationship to insulin sensitivity and family history of non-insulin-dependent diabetes mellitus.
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Academic Article
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Moderate effect of duodenal-jejunal bypass surgery on glucose homeostasis in patients with type 2 diabetes.
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Academic Article
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Defects in insulin secretion and action in women with a history of gestational diabetes.
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Academic Article
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Targeted ablation of glucose-dependent insulinotropic polypeptide-producing cells in transgenic mice reduces obesity and insulin resistance induced by a high fat diet.
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Academic Article
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Insulin secretion in insulin-resistant women with a history of gestational diabetes.
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Academic Article
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Maturity-onset diabetes of the young.
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Academic Article
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Familial hyperinsulinemia due to a structurally abnormal insulin. Definition of an emerging new clinical syndrome.
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Academic Article
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Basal insulin hypersecretion in insulin-resistant Zucker diabetic and Zucker fatty rats: role of enhanced fuel metabolism.
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Academic Article
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Abnormal insulin secretion, not insulin resistance, is the genetic or primary defect of MODY in the RW pedigree.
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Academic Article
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Ginseng and ginsenoside Re do not improve ß-cell function or insulin sensitivity in overweight and obese subjects with impaired glucose tolerance or diabetes.
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Academic Article
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Relative effects of calorie restriction and weight loss in noninsulin-dependent diabetes mellitus.
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Academic Article
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BH3-only molecule Bim mediates ß-cell death in IRS2 deficiency.
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